For the first time this season, Thomas Tuchel was able to field his Fantastic Four - Neymar, Mbappe, Icardi and Angel Di Maria - at the front and it was rewarded with a comfortable victory.
In the 33rd minute Fati's acceleration then drew a foul in the area from Mario Gaspar and Messi slotted home the penalty to make it 3-0 and Pau Torres scored an own goal with the last action of the first half when he put Messi's clipped ball past the stranded Asenjo under timid pressure from Busquets.
China's General Administration of Sports has listed the tournament as one of six major sports events during the "Golden Week" holiday.
Autuori led Botafogo to six victories, 13 draws and four defeats after taking charge of the two-time Serie A champions for a fifth time in February.
Brazil's Gremio also secured their place in the tournament's next phase on Tuesday, with a 2-0 home win over Chilean side Universidad Catolica. Pepe and Antonio Rodrigues were on the scoresheet for the Porto Alegre outfit.
Born in the Netherlands, Dest had had a contract at Ajax until mid-2022.
There was last second drama as Manchester United got their first win of the season with a 3-2 victory away to Brighton on Saturday thanks to a penalty given after the final whistle.
"I am just trying my best every single day. I am working hard in every practise to try to be better and better in every match," Nadal said,"Today was not that cold, so that's the main thing, the conditions are not that bad."
"We are a team under construction and we didn't have time to try more solutions in the pre-season, so let's try to find them in these first few games," he added.
The 27-year-old Mokua, who holds personal best of 1:02:50 in the half marathon, suffered four broken ribs and a double fracture on his left hand during the incident in Nyahururu, some 190km from the capital Nairobi.
"This will ensure that sportspersons, coaches, media and spectators are kept safe and healthy," President Kenyatta said.